Studies on Acetylenic Compounds. XXIV

Boronic acid catalyzed ene carbocyclization of acetylenic dicarbonyl compounds.

The discovery and development of an efficient ene carbocyclization of 1,3-dicarbonyl compounds bearing pendent terminal alkyne substituents under 3-nitrobenzeneboronic acid catalysis is described. The reaction is efficient, easy to perform and general to a wide range of ketoester substrates.

New acetylenic norlignan compounds from rhizomes of Curculigo crassifolia.

Two pairs of diastereoisomeric acetylenic norlignan compounds with PhCH(OR(1))CH(OR(2))CH(2)C triple bond CPh skeleta: (1R, 2R)-1-O-methylnyasicoside (1) and (1S, 2R)-1-O-methylnyasicoside (2), and (1R, 2R)-crassifogenin D (3) and (1S, 2R)- crassifogenin D (4), were isolated from the ethanolic extract of rhizomes of Curculigo crassifolia. Compounds 3 and 4 are new and their structures were eluc...

Studies on Uric Acid and Related Compounds

The systematic study of the substrate specificity of mammalian xanthine oxidase has indicated a common mechanism by which various purines may be dehydrogenated (1). The results obtained also made it clear why methylated xanthines, with the exception of 1-methylxanthine (2), cannot be oxidized by xanthine oxidase to the corresponding substituted uric acids (3, 4). Therefore, another source had t...

Regulation of erythropoiesis (XXIV). Studies on the post-hypoxic "rebound" phase.

Meeting of Minds XXIV

#1 Title: Music Therapy: An intervention for psychiatric patients and their health care staff Author: Emily Meihls Faculty sponsor: Maureen Thum Affiliation: Honors Program, University of Michigan-Flint Abstract: Music therapy has been developing for several decades, and in recent years has been formally recognized as a highly accredited profession. This non-traditional therapy has been impleme...